AHK-Cu 10 mg

AHK-Cu is the copper(II) complex of the tripeptide L-alanyl-L-histidyl-L-lysine. It is a close structural relative of GHK-Cu, the copper-binding tripeptide found in human plasma, and shares its histidine-mediated copper coordination. AHK-Cu is used in cell-culture research alongside GHK-Cu, most often in dermal fibroblast and hair-follicle dermal papilla cell models.

Each vial contains 10 mg of lyophilized AHK-Cu.

Note: AHK-Cu is for research use only. Not for human consumption.

AHK-Cu Mechanism of Action (Based on Research)

Copper Delivery and Coordination Chemistry

Like GHK-Cu, the peptide chelates copper(II) through the histidine imidazole and the N-terminal amine. Research on the complex focuses on how peptide-bound copper is presented to cultured cells compared with free copper salts.

Dermal Papilla Cell Studies

Published in vitro work characterizes changes in proliferation markers and vascular endothelial growth factor (VEGF) expression in cultured dermal papilla cells exposed to AHK-Cu, which is the observation most associated with the compound.

Fibroblast and Extracellular Matrix Models

Fibroblast cultures are used to compare AHK-Cu with GHK-Cu on extracellular-matrix gene expression, providing a structure-activity comparison between the two copper tripeptides.

AHK-Cu Research Applications

AHK-Cu is used in copper-peptide structure-activity studies, dermal papilla and fibroblast cell-culture models, and as a comparator to GHK-Cu in extracellular-matrix research.

AHK-Cu Peptide Characteristics

• Peptide Sequence: Ala-His-Lys (AHK), complexed with copper(II)
• Synonyms:
  • Copper tripeptide AHK
  • L-alanyl-L-histidyl-L-lysine copper complex
• Appearance: blue lyophilized powder (copper complex)
• Vial Contents: 10 mg lyophilized powder
• Storage Recommendations:
  • Lyophilized powder: store at -4 °F (-20 °C) for long-term storage (stable for up to 3 years); short-term storage at 39 °F (4 °C) (up to 2 years). Keep sealed, dry, and away from light.
  • In solution: store at 39 °F (4 °C) for short periods, or at -4 °F (-20 °C) for longer durations. Avoid repeated freeze-thaw cycles. Use sterile technique when handling.

Certificate of Analysis (COA)

Independent third-party testing for this product is in progress. The batch Certificate of Analysis will be published here as soon as it is available. Contact our support team at any time to ask about its status before ordering.

Legal Disclaimer

This product is intended strictly for laboratory research purposes only. It is not approved by the FDA or any other regulatory agency for human consumption, medical use, or veterinary application.

• • Not for diagnostic, therapeutic, or clinical use.
  • Not intended for resale or use in food, drugs, cosmetics, or household items.
• Not intended for ingestion, injection, or application to humans or animals, and should never be used in any form of self-experimentation.

By purchasing from Evolve Peptides, the buyer agrees to use it in accordance with all applicable laws, regulations, and research safety protocols.